Apr 3, 2000 · A proposed model for the histogenesis of B cell lymphoma. The model is derived from the mutation pattern of Ig and BCL-6 genes (identified by ...
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Apr 19, 2022 · MUM1 / IRF4 is the abbreviation of multiple myeloma 1 / interferon regulatory factor 4 · Normally expressed in plasma cells, melanocytes, ...
MUM1/IRF4 protein plays a positive regulator role in transcription, using its C-terminal transactivation domain.27 Although the exact physiologic function is ...
MUM1 is a gene primarily identified in Multiple Myeloma cell line where it was localized in region of chromosomal translocations t(6;14)(p25;q32) placing this ...
Abstract. MUM1/IRF4 protein is a member of the interferon regulatory factor (IRF) family of transcriptional factors initially described as downstream regulators ...
MUM1 is induced by antigen receptor-mediated stimuli and plays a crucial role in cell proliferation, differentiation and survival (5). Loss of MUM1 function ...
MUM-1 (multiple myeloma oncogene-1), expressed by the IRF4 gene, is seen in a subset of B cells in the light zone of the germinal center (representing late ...
Mar 15, 2000 · A new monoclonal antibody (MUM1p) was used to study the cell/tissue expression of human MUM1/IRF4 protein, the product of the homologous ...
Sep 28, 2015 · Immunostaining with CD10, B-cell lymphoma 6 (BCL6), and multiple myeloma oncogene 1 (MUM1) in diffuse large B-cell lymphoma conventional smears.
Jul 1, 2001 · The gene encoding MUM1 was characterized as a possible translocation partner in chromosomal abnormalities involving a significant number of ...