The MED12 gene provides instructions for making a protein called mediator complex subunit 12. As its name suggests, this protein forms one part (subunit) of the mediator complex, which is a group of about 25 proteins that work together to regulate gene activity.
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Apr 16, 2024 · MED12 Regulates Human Adipose-Derived Stem Cell Adipogenesis and Mediator Kinase Subunit Expression in Murine Adipose Depots. MED12 Regulates ...
Apr 1, 2013 · The MED12 gene provides instructions for making a protein called mediator complex subunit 12. Learn about this gene and related health ...
Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome.
MED12
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Mediator of RNA polymerase II transcription, subunit 12 homolog, also known as MED12, is a human gene found on the X chromosome. Wikipedia
Cellular component: membrane; ubiquitin ligase complex; mediator complex; nucleus; nucleoplasm
MED12 (Mediator Complex Subunit 12) is a Protein Coding gene. Diseases associated with MED12 include Opitz-Kaveggia Syndrome and Intellectual Developmental ...
Mediator is a multiprotein complex that can function in transcriptional activation or repression depending on the factors with which it interacts.
MED12 is involved in a variety of cellular activities, and mutations in MED12 gene impair MED12 activities and are associated with several diseases, including ...
Recurrent missense mutations in the RNA polymerase II Mediator subunit MED12 are associated with X-linked intellectual disability (XLID) and multiple ...
Most boys with MED12 related disorders have intellectual disability/ developmental delay, behavioural problems and low muscle tone. MED12 related disorders ...
Jul 10, 2023 · MED12 mutations lead to enhanced expression of collagen genes in 3D culture conditions. Fibroid tumors are known to have an aberrantly remodeled ...