Aims: The main objective is to evaluate the value of tumor MGMT promoter (pMGMT) methylation in the prediction of the objective response (OR) at 3 months in ...
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May 9, 2023 · O6-methylguanine-DNA methyltransferase (MGMT) has been linked with alkylating agent resistance and tumor growth suppression.
MGMT is the main enzyme responsible for the repair of O6meG lesions in DNA induced by alkylating agents in NETs. Increasing arguments advocate that MGMT ...
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