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Drotaverine
Drug
AHFS/Drugs.com: International Drug Names
ATC code: A03AD02 (WHO)
Bioavailability: Highly variable (~65%), peak at 45–60 min
Elimination half-life: 7–16 hours
Excretion: >50% in urine and ~30% in bile
Metabolism: Hepatic
Protein binding: 95–98%
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Sep 7, 2010 · Drotaverine is a phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
This study shows that, in patients with IBS, treatment with drotaverine HCl 80 mg given three times daily for 4 weeks is more effective than placebo in reducing ...
Jun 1, 2022 · The GPs perceived drotaverine as more useful, effective, and tolerable than other drugs for abdominal pain or cramps. Drotaverine significantly ...
Drotaverine is a spasmodic treatment that alleviates contractions (spasms) in the abdomen in connection with smooth muscles. Diclofenac is an anti-inflammatory ...
Nov 17, 2021 · It works by reducing the contraction of smooth muscles. Drotaverine has some side effects like nausea, vomiting, dry mouth, dizziness, etc.
Jun 10, 2022 · Drotaverine is an anti-spasmodic medicine which relieves contractions (spasms) associated with smooth muscles in the abdomen. Common side ...
Drotaverine is an important treatment for twitches or spasms of the smooth muscles of the stomach and heart. It relieves pain caused by irritable bowel syndrome ...
Drotaverine Hydrochloride: Uses, Dose, Side Effects and Cost
www.pacehospital.com › drotaverine-hy...
Primarily drotaverine hydrochloride tablet is used to treat smooth muscle contractions which is felt as recurrent stomach pain in the gastrointestinal tract.
Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). It is a benzylisoquinoline derivative that is structurally related to ...