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Okazaki fragments are short sequences of DNA nucleotides which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create ...
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Thus, this Okazaki fragment duplex assumes a conformation in solution that is a chimeric mixture of hybrid-form (H-form) and B-form structures and the overall ...
Feb 15, 2019 · In a 1968 paper in PNAS, Reiji and Tsuneko Okazaki and colleagues (1) proposed that the lagging strand is replicated discontinuously in the form ...
Jul 22, 2022 · Unligated Okazaki fragments are a major source of DNA single-strand breaks in eukaryotic cells. Cells activate DNA damage response checkpoints ...
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This enzyme recognizes the trinucleotide sequence d(CTG) within the DNA template and uses two of those nucleotides to direct the synthesis of the first ...
Our data support a model for Okazaki fragment processing where the strand displacement activity of DNA polymerase δ is modulated by the concerted action of PCNA ...
Video for okazaki-DSTART
Aug 9, 2021 · ... start stations” for the copying machinery ... start stations” for the copying machinery. ... Tsuneko ...
Duration: 18:42
Posted: Aug 9, 2021
Okazaki fragments are small sections of DNA that are formed during discontinuous synthesis of the lagging strand during DNA replication.
Nov 15, 2022 · The final steps of lagging strand synthesis induce maturation of Okazaki fragments via removal of the RNA primers and ligation.