Apr 3, 2024 · This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger.
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Apr 10, 2015 · We have identified ING5 as a novel CDK2 substrate. ING5 is phosphorylated at a single site, threonine 152, by cyclin E/CDK2 and cyclin A/CDK2 in ...
ING5 is a core component of two different HAT complexes: MOZ/MORF or HBO1 complexes (also known as the KAT6A/6B and KAT7 complexes) (19). These complexes ...
Oct 5, 2022 · The ING (inhibitor of growth) family is composed of ING1–5, and involved in apoptosis, senescence and DNA damage. They function as epigenetic ...
Inhibitor of growth protein 5 is a protein that in humans is encoded by the ING5 gene. ING5. Available structures. PDB, Ortholog search: PDBe RCSB ...
ING5 is a dimeric protein that contains two identical PHD fingers that recognize histone H3K4me3 with a Kd in the micromolar range. The dimerization site is at ...
This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger.
Oct 16, 2018 · Inhibitor of growth family 5 (ING5) is a member of the ING protein family and functions as a type-II tumor suppressor gene. Human ING5 is mapped ...
May 10, 2017 · In conclusion, this study demonstrated that ING5 can suppress the proliferation and invasion of, and stimulate the apoptosis of breast cancer ...
Apr 4, 2023 · Human ING5 belongs to the ING family of tumor suppressors that control the cell cycle, cell growth, and apoptosis (21, 22), and its ...