In this study, we examined whether transferrin receptor (Tf-R) targeted liposomes can efficiently deliver encapsulated doxorubicin (DXR) into MDR cells (SBC-3/ ...

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CsA inhibits the efflux of antitumor agents through their binding to P-gp, resulting in intracellular accumulation of the antitumor agents and so overcomes drug ...

Abstract. Notch signaling regulates cell-fate decisions during development and postnatal life. Little is known, however, about the role of Delta-like-4.

Nov 3, 2003 · Parathyroid hormone-related protein (PTHrP) is responsible for production of bone metastasis, but not visceral metastasis, by human small cell ...

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Small cell lung cancer (SCLC) is aggressive, with rapid growth and frequent bone metastasis; however, its detailed molecular mechanism remains poorly ...

Mar 2, 2018 · The results demonstrated that upregulation of DKK1 in SBC‑3 cells enhanced cell proliferation, colony formation, cell migration and invasion in ...