Jan 3, 2017 · TTN gene truncating variants are common in dilated cardiomyopathy (DCM), although data on their clinical significance is still limited.
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Transient tachypnea of the newborn (TTN) is a benign, self-limited condition that can present in infants of any gestational age, shortly after birth.
Nov 27, 2019 · In healthy hearts, the TTN N2B isoform is predominant and the TTN N2BA isoform is less expressed (Nagueh et al., 2004). N2B is a comparatively ...
Mar 4, 2024 · Myosin binding protein C mutations and compound heterozygosity in hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 44(9), 1903–1910 (2004).
Jan 16, 2024 · Titin (TTN) is one of the largest and most complex proteins expressed in humans, and truncation variants are the most prevalent genetic ...
Titin, or connectin, is a giant muscle protein expressed in the cardiac and skeletal muscles that spans half of the sarcomere from Z line to M line.
Dec 14, 2021 · Background:Titin truncation variants (TTNtvs) are the most common inheritable risk factor for dilated cardiomyopathy (DCM), a disease with ...
Abstract. The giant sarcomere protein titin is a major determinant of cardiomyocyte stiffness and contributor to cardiac strain sensing. Titin-based forces.
Sep 2, 2008 · Aim: Transient tachypnea of the newborn (TTN) is a common cause of early respiratory distress in the neonatal period of term infants.
TTN is one of the largest human genes, with 363 exons. It encodes titin, a huge muscle protein that covers half of the sarcomere from the Z-line to the M-line, ...